Minimizing the Likelihood of Drug Resistant Micro-organisms

The evolution and spread of drug resistant pathogens presents a growing problem worldwide.  The fact that virtually all anti-microbials lose efficacy over time because of the development and spread of resistance in the target organism could be greatly reduced by creating novel and affordable approaches to optimal drug delivery tools.
People Impacted
$ 1.2T
Potential Funding
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the problem
Nature and Context

We lack an understanding of the key determinants of the evolution and spread of resistance, and we lack the ability to slow the emergence of resistant variants.This means we need too develop novel technologies and approaches to slow the evolution and spread of drug resistance.  These include novel drug delivery technologies; the identification of drug targets less susceptible to selection under drug pressure, including targets that control disease not infection; targets in the host; and targets involved in the transfer of genetic materials within pathogen population.

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